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Hobart W. Harris, M.D., M.P.H.


Hobart W. Harris, M.D., M.P.H.

Professor of Surgery
Chief, Division of General Surgery

 

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General Surgery »  Faculty »  Hobart W. Harris, M.D., M.P.H.

Hobart W. Harris, M.D., M.P.H.

Professor and Chief, Division of General Surgery
J. Engelbert Dunphy Endowed Chair in Surgery

Contact Information

513 Parnassus Avenue

San Francisco, California 94143-0104

Clinical Telephone: (415) 353-2161

New Patient Coordinator Telephone: (415) 353-2804

Academic Telephone: (415) 514-3891

Fax: (415) 476-0164

e-mail: harrish@surgery.ucsf.edu

Education

  • 1975-1979 Harvard College, Cambridge, MA             A.B. Biology
  • 1979-1983 Harvard Medical School, Boston, MA         M.D. Medicine
  • 1983-1984 Harvard School of Public Health, Boston, MA  M.P.H. General Studies

Residencies

  • 1984-1985 University of California, San Francisco Intern Surgery
  • 1985-1993 University of California, San Francisco Resident Surgery

Fellowships

  • 07/1993-12/1993 University of Hong Kong, Queen Mary Hospital, Hong Kong, P.R.C. Hepatobiliary Surgery
  • 02/2005-07/2005 University of Louisville, Louisville, KY ERCP

 

Postdoctoral Training

Board Certification

  • American Board of Surgery, 1994

Program Affiliations

Clinical Expertise

  • Acute Pancreatitis
  • Bile Duct Injuries
  • Cancer Surgery
  • Chronic Pancreatitis
  • Gall Bladder Disease
  • Gastrointestinal Cancer
  • Gastrointestinal Surgery
  • Intra-abdominal Sepsis
  • Pancreas Surgery
  • Pancreatic Cancer
  • Soft Tissue Infections

Research Interests

Biography

Dr. Hobart W. Harris is Chief of the Division of General Surgery, Vice-Chair of the Department of Surgery, and a Professor of Surgery at the University of California, San Francisco. Dr. Harris is also a Principal Investigator in the UCSF Surgical Research Laboratory at San Francisco General Hospital.

Dr. Harris is an expert in treating surgical infections and diseases of the pancreas and biliary system. His areas of expertise include pancreas and bile duct cancer, acute and chronic pancreatitis, gallstone disease, intra-abdominal sepsis and serious infections of the skin and soft tissue.

Dr. Harris earned his undergraduate, medical and public health degrees at Harvard University, then completed an internship and residency in surgery at UCSF. After residency training, he completed a fellowship in heptobiliary surgery at the University of Hong Kong, Queen Mary Hospital and joined UCSF in 1994.

His research focuses on surgical infections, innate immunity and inflammatory diseases of the pancreas. His laboratory work is supported by an NIH grant to study the role of triglyceride-rich lipoproteins in the innate host response to endotoxins, such as those released by the Gram-negative bacteria that cause the most deadly form of sepsis.

Dr. Harris is a fellow of the American College of Surgeons and is a member of numerous surgical and scientific societies including the American Surgical Association and the International Hepato-Pancreato-Biliary Association.

 

Selected Publications

TOP 5 PUBLICATIONS  

  1. Harris HW, Grunfeld C, Feingold KR and Rapp JH. Human VLDL and chylomicrons can protect against endotoxin-induced death in mice. J Clin Invest. 86: 696-702, 1990.
  2. Harris HW, Grunfeld C, Feingold KR, Read TE, Kane JP, Jones AL, Eichbaum EB, Bland GF and Rapp JH. Chylomicrons alter the fate of endotoxin, decreasing tumor necrosis factor release and preventing death. J Clin Invest. 91: 1028-1034, 1993.
  3. Harris HW, Johnson JA, Wigmore SJ. Endogenous lipoproteins impact the response to endotoxin in humans. Crit Care Med. 30: 23-31, Jan/2002.
  4. Kasravi FB, Welch WJ, Peters-Lideu CA, Weisgraber KH, Harris HW. Induction of cytokine tolerance in rodent hepatocytes by chylomicron-bound LPS is low-density lipoprotein receptor dependent. Shock. 19: 157-62, Feb/2003.
  5. Spitzer AL, Barcia AM, Schell MT, Barber A, Norman J, Grendell J, Harris HW. Applying Ockham's razor to pancreatitis prognostication: a four-variable predictive model. Ann Surg. 243: 380-8, Mar/2006.